A clinical study on the treatment of postherpetic neuralgia with pulsed radiofrequency of the dorsal root ganglion with pain management [2020] - 207KB
by Zhi-Hong Xiong, Xue-Fang Tang, Le-Tian Huang, Li-Rong Yue
This study aimed to investigate the clinical efficacy of pulsed radiofrequency (PRF) of the dorsal root ganglion (DRG) with pain management as treatment of post-herpetic neuralgia (PHN). A total of 78...

Differential expression of circulating miRNAs in Parkinson’s disease patients: Potential early biomarker? [2020] - 1,264KB
by Siti Aishah Sulaiman, Nor Ilham Ainaa Muhsin, Ahmad Rasyadan Arshad, Wan Fahmi Wan Mohamad Nazarie, Rahman Jamal, Norlinah Mohamed Ibrahim, Nor Azian Abdul Murad
Background & Objective: Circulating microRNAs (miRNAs) expressions have been suggested as potential biomarkers for Parkinson’s Disease (PD). Identification of early biomarkers for PD is important an...

Emodin ameliorates diabetic neuropathic pain through inhibiting up-regulation of TRPV1 and pro-inflammatory cytokines in dorsal root ganglions in rats [2020] - 720KB
by Ya-Fang Chen, Yin-Hui Huang, Mei-li Yang, Zhi-Qiang Lin
Background & Objective: Peripheral neuropathy is one of the most common complications of diabetes and leads to sensory symptoms, including diabetic neuropathic pain (DNP). Emodin has potential analges...

Periodontal disease and cognitive deficits: A systematic review and meta-analysis [2020] - 7,031KB
by Ting Wang, Qian Zhang, XinQiang Liu, Lei Ma, Jing Fu, Yuli Gao, Chunmiao Jiang, Dapeng Ren
Background: Previous studies showed controversial findings for correlation of periodontal disease and cognitive deficits. Methods: We searched systematically for studies pertaining to correlation of p...

Auraptene has neuroprotective and memory enhancing effects in a rat model of Alzheimer’s disease [2020] - 667KB
by Sadri Joghataee, Mohammad Mohammad-zadeh, Bahareh Amin, Faranak Jafari, Mahdi Tondar, Omid Gholami
Background: Auraptene is a simple coumarin that exhibits multiple protective activities in the brain. Alzheimer’s disease is a complex, multifactorial, and progressive neurodegenerative disease. Mic...

Evaluation of plasma soluble CD137 level in relapsing-remitting multiple sclerosis patients in comparison with healthy controls in Isfahan Province, Iran [2020] - 356KB
by Morteza Jafarinia, Mehnoosh Ashja-Arvan, Fahimeh Hosseininasab, Sina Vakili, Erfan Sadeghi, Masoud Etemadifar, Fereshteh Alsahebfosoul
Objective: Multiple sclerosis (MS) is a chronic neuroinflammatory disease, characterizes by demyelination in the central nervous system (CNS). Co-stimulatory molecules such as CD137 (4-1 BB) play a ma...

Neurophobia among family medicine specialist trainees in Malaysia [2020] - 289KB
by Leng Yien Chua, Normaskinah Yahya, Sharifah Hanim Syed Khairuddin, Nor Faizah Mohamad, Pusparani Jaganathan, Fan Kee Hoo, Wan Aliaa Wan Sulaiman, Siew Mooi Ching, Kai Wei Lee
Background: Neurophobia is defined as the fear of neural sciences and clinical neurology. Our study aims to determine the prevalence and factors associated with neurophobia among family medicine speci...

The effects of implementation of neurological intensive care sub-specialized module on doctors satisfaction, nurses’ competency and patient’s outcome [2020] - 344KB
by Min Hu, Zhuo Fu, Min Zhou
Objective: This study aimed to evaluate the effects of implementation of a neurological sub-specialized nursing module in critically ill neurological patients. Methods: We selected 22 neurological nur...

Thrombolysis may be safely given in an acute stroke patient with Marfan’s syndrome: A case report [2020] - 923KB
by Yexian Jonathan Lai, Oh Chia Theng Daniel Oh
Marfan’s syndrome is a systemic disorder of connective tissue typically involving cardiovascular, musculoskeletal and ocular systems. Given the relative rarity of neurovascular complications in Marf...

Ryanodine receptor 2 mutation: Not only catecholaminergic polymorphic ventricular tachycardia but also epileptiform discharges in electroencephalogram [2020] - 3,036KB
by Yingfang She, Yide Li, Hang Yu, Liemin Zhou
Ca2+ leak via ryanodine receptor type 2 (RyR2) can cause potentially fatal arrhythmias, and RyR2 mutations have been shown in the aetiology of catecholaminergic polymorphic ventricular tachycardia. We...