Altered expression of potassium channel genes in familial hypokalemic periodic paralysis [2011] - 303KB
by JB Kim, GM Lee, SJ Kim, DH Yoon, YH Lee
We analyzed the mRNA expression patterns of major potassium channel genes to determine the mechanism of hypokalemia in familial hypokalemic periodic paralysis. We used quantitative RT-PCR to examine t...

No correlation between COMT genotype and entacapone benefits in Parkinson’s disease [2011] - 247KB
by JS Kim, JY Kim, JM Kim, JW Kim, SJ Chung, SR Kim, MJ Kim, HT Kim, KG Choi, DI Shin, YH Sung, KS Lee, HJ Kim, J Cho, MY Park, HY Park, SM Choi, KW Park, HW Lee, TB Ahn, OD Kwon, SJ Kim, BS Jeon
Catechol-O-methyltransferase (COMT) inhibitors are used to increase the bioavailability of therapeutic L-dopa. We examined the efficacy of entacapone in Parkinson’s disease patients who had daily â€...

Plasma non-esterified fatty acids in patients with multiple sclerosis [2011] - 316KB
by GM Hon, MS Hassan, SJV Rensburg, S Abel, RT Erasmus, T Matsha
Objective: The purpose of this study was to investigate the levels of non-esterified fatty acids in plasma from patients with multiple sclerosis and further to correlate these findings with the neurol...

Oral riboflavin versus oral propranolol in migraine prophylaxis: An open label randomized controlled trial [2011] - 260KB
by NJ Nambiar, C Aiyappa, R Srinivasa
Background: Migraine is a chronic, often debilitating disease. The treatment of migraine with propranolol (80-240 mg/day) is limited by side effects and lack of tolerability. Riboflavin (vitamin B2) i...

Restorative therapy using autologous bone marrow derived mononuclear cells infusion intra-arterially in patients with cerebral palsy: An open label feasibility study [2011] - 829KB
by MV Padma Srivastava, A Bhasin, S Mohanty, S Sharma, U Kiran, CS Bal, S Gaikwad, MB Singh, R Bhatia, M Tripathi, K Prasad, S Singh, V Goyal, G Shukla, M Behari
Cerebral Palsy is a common and devastating neurological disorder, with no medical treatment apart from physiotherapy regimes to alleviate the functional disability. Regenerative medicine using stem ce...

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis: A series of ten cases from a university hospital in Malaysia [2011] - 216KB
by S Abdullah, SY Lim, KJ Goh, LCS Lum, CT Tan
Objective: To report on the incidence, and the clinical and laboratory features of patients seen at the University of Malaya Medical Centre with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis...

Contralateral stroke with rapid recovery in a patient of herpes zoster ophthalmicus [2011] - 863KB
by R Verma, D Singh, P Sharma
Herpes zoster ophthalmicus commonly presents with vesicular eruptions of skin along a dermatome and post herpetic neuralgia. Viral invasion into the intracranial vessel and resultant arteritis is rare...

Pantothenate kinase associated neurodegeneration (PKAN) presenting as a seizure disorder [2011] - 184KB
by HP Sinha, M Modi, S Prabhakar, M Khanal
Pantothenate kinase associated neurodegeneration (PKAN) is an uncommon degenerative disease of the basal ganglia caused by mutations in the PANK2 gene. We describe a 19-years-old man with clinically a...

Karaoke, power failure and carbon monoxide poisoning [2011] - 248KB
by CH Chai, SY Lim, KAA Kadir, KJ Goh, CT Tan
Accidental carbon monoxide poisoning in countries with cold climates is commonly related to indoor heating. This condition appears to be relatively uncommon in tropical Asian countries and therefore t...

Herpes zoster oticus masquerading as lateral pontomedullary syndrome [2011] - 682KB
by PA Shah, HB Khan, Y Yaseen, AH Malik, I Hassan
Ramsay Hunt syndrome, also known as herpes zoster oticus is usually caused by reactivation of pre-existing varicella zoster virus in the geniculate ganglion. Here we report a case of herpes zoster oti...