Imaging findings of an isolated deep cerebral venous thrombosis in the absence of superficial sinus thrombosis [2015] - 1,970KB
by Sabrilhakim Sidek, Kartini Rahmat, Norlisah Ramli
Thrombosis of the deep cerebral venous system in the absence of superficial sinus thrombosis is a very rare disease. The clinical and radiological findings can be diagnostically challenging due to the...

Diagnosis of X-Linked creatine transporter deficiency in a patient from Northeast China [2015] - 618KB
by Chun-Hui Hu, Yu-Ying Fan, Long-Fei Wang, Tao Yu, Xiao-Ming Wang, Hua Wang
Background: Creatine transporter (CRTR) deficiency is the most common creatine deficiency syndrome, of which the final diagnosis relies on mutation in the X-linked CRTR gene. To date, more than 90 mut...

Spontaneous temporosphenoidal meningoencephalo cele as a rare cause of non-traumatic cerebrospinal fluid rhinorrhoea [2015] - 465KB
by Bushra Johari, Hazman Mohd Nor, Gnana Kumar, Prepageran Narayanan
Cranial encephaloceles are rare conditions, which are more commonly seen in the anterior rather than in the middle cranial fossa. Temporal lobe encephalocele can present with a variety of clinical sym...

Need for ‘teratovigilance’ in women with epilepsy on anti-epileptic drugs [2015] - 152KB
by Chanda Kulkarni, GRK Sarma, S Dwajani S, F Errol, CN Sheela
‘Off label’ use of many newer anti-epileptic drugs (AEDs) has been approved for treatment of epilepsy with a parallel increase in their use for non-epileptic conditions over the last decade.1 The ...

Intravenous administration of EGB 761 and 90-day functional outcome in patients with acute ischemic stroke [2015] - 411KB
by Dong-Ick Shin, Hyung-Suk Lee, Shin-Hye Baek, Ho-Seong Han, Hye-Lim Lee, Yong-Dae Kim
Background & Objective: EGB 761 is a standardized natural extract used to treat impaired cerebral perfusion and nutrition (cerebrovascular insufficiency) in Korea. Although several animal studies have...

Lack of association between ABCC2 polymorphisms and plasma carbamazepine concentrations or pharmacoresistance in Chinese patients with epilepsy [2015] - 304KB
by Zhuo Wan, Hongmei Meng, Yan Bai, Yi Bai, Yang Dong, Min Liang, Yingjie Guo
Multidrug resistance proteins (MRP2, ABCC2) may play a role in drug resistance in epilepsy by limiting gastrointestinal absorption and brain access of antiepileptic drugs (AEDs). We sought to investig...

Bone mineral density and urinary hydoxyproline are already abnormal in newly diagnosed patients with epilepsy in this North Indian study [2015] - 307KB
by Kiran Dahiya, Aastha Bansal, Surekha Dabla, Rakesh Dhankhar, Veena Singh, Himanshu Devender Kumar, Deepika Dalal
Background & Objective:Epilepsy may have an impact on bone health of the patients even before drug therapy is initiated, particularly in the developing countries. This is in view of long delay in diag...

Factors affecting adherence to antiepileptic drugs therapy in Malaysia [2015] - 325KB
by X C Tan, M Makmor-Bakry, C L Lau, F W Tajarudin, A A Raymond
Poor adherence to antiepileptic drug (AED) therapy can lead to various undesirable complications. Identifying the contributing factors of poor adherence is beneficial in assisting health care professi...

Do cytokines correlate with disease activity in tuberculous meningitis? [2015] - 461KB
by Human P Sinha, Manish Modi, Sudesh Prabhakar, Paramjit Singh
Background: Tuberculous meningitis (TBM) remains to be one of the most fatal central nervous system infections. The exact pathogenesis of TBM at cellular level remains unclear. In this study, we asses...

Parkinson’s disease and risk of pancreatic cancer: a population-based case-control study in Taiwan [2015] - 335KB
by Kuan-Fu Liao, Cheng-Li Lin, Shih-Wei Lai, Wen-Chi Chen
Background: The aim of this study was to investigate whether there is a relationship between Parkinson’s disease and pancreatic cancer in Taiwan. Methods: This was a case-control study using claim d...