Effect of antipsychotics in epilepsy patients with psychiatric symptoms [2010] - 68KB
by M Okazaki, M Ito, M Kato, M Watanabe, Y Watanabe, T Onuma
Background and Objective: Psychiatric co-morbidity in epilepsy patients is common, often requiring the use of antipsychotic drugs. However, antipsychotics may not be administered at dosages adequate f...

Intravenous sodium valproate for diazepam refractory convulsive status epilepticus [2010] - 79KB
by L Chen, P Feng, B Zhou, J Li, J Wang, L Liu, D Zhou
Background and Objective: Convulsive status epilepticus (SE) is the most common and life-threatening form of SE. Treatment for SE differs greatly from the United States and Europe. For refractory SE, ...

Metabotropic glutamate receptor 5 antagonist, two-methyl-6-phenylethynyl-pyridine (MPEP), with low doses of MK801 and diazepam: A novel approach for controlling status epilepticus [2010] - 79KB
by FR Tang, PM Chen, YC Tang, MC Tsai, WL Lee
Background and Objective: Status epilepticus (SE) is the most severe and feared form of epilepsy. The overall incidence of SE varies from 10 to 60 per 100,000 person-years, and the mortality is approx...

Surgical outcome and prognostic factors of temporal lobe epilepsy [2010] - 70KB
by G Luan, X Dong, Y Li
Objective: To analyzing the long-term results of temporal lobe epilepsy (TLE) surgery in our Center, and to evaluate factors that are related to the outcome. Methods: 93 consecutive patients of TLE wh...

Surgical results of corpus callosotomy for intractable epilepsy with West syndrome [2010] - 70KB
by H Baba, T Ono, K Toda, K Ono, S Baba
Background and Objective: Infants with West syndrome are at high risk for developing severe mental retardation. Pinard et al1 reported dramatic reduction of spasms in patients with West syndrome after...

Quality of life after resective surgery for intractable mesial temporal lobe epilepsy and neocortical epilepsy [2010] - 76KB
by K Hino, T Otsuki, T Kaido, A Takahashi, S Watanabe, M Muyajima, K Hara, M Watanabe, Y Watanabe
Background and Objective: Intractable epilepsy patients have multiple handicaps which are associated with the epilepsy itself or with etiologies of epilepsy. In general, the clinical manifestations of...

A community study on the factors associated with quality of life of people with epilepsy in Hong Kong [2010] - 80KB
by ATF Hung, R Fielding, P Kwan, E Yu, D Yu, A Jacoby, G Baker, GCY Fong
Background and Objectives: Epilepsy is a common neurological disorder. People with epilepsy (PWE) are not only confronted with a medical condition, but also many psychosocial repercussions which may a...

Neuropsychological assessment in epilepsy surgery: Preliminary experience in a rural tertiary care hospital in North East Malaysia [2010] - 69KB
by S Sayuthi, J Tharakan, Maria, WM Salmah, S Madhaven, A Tahir, J George, Jafri
Background: We present our preliminary experience into neuropsychological testing in epilepsy surgery patients to demonstrate how these tests contributed to decide the laterality of epileptic focus, a...

Changes in psychiatric comorbidity during early post-surgical period in patients operated for medically refractory epilepsy: a MINI based follow-up study [2010] - 91KB
by SD Desai, G Shukla, S Singh, V Goyal, MV Padma, M Tripathi, A Srivastava, M Singh, P Sharatchandra, A Gupta, K Shivakumar, R Sagar, S Gaikwad, A Garg, CS Bal, M Behari
Background and Objective: Psychiatric disorders are described to co-exist, appear de-novo after surgery, or improve after surgery, in patients undergoing surgery for refractory epilepsy. We initiated ...

Two single nucleotide polymorphisms in SCN1A of Chinese GEFS+ patients [2010] - 1,104KB
by M Gao, Y Shi, W Deng, M Yu, L Chen, W Liao
Objective: Recent studies have provided evidence that mutations in SCN1A represent the most frequent cause of generalised epilepsy with febrile seizures plus (GEFS+). Whether the variation of SCN1A si...