Withdrawal of antiseizure medications in patients who are seizure-free [2024] - 252KB
by Can Ulutaş, Buse Rahime Hasırcı Bayır, Yılmaz Çetinkaya, Kemal Tutkavul
Objective: To evaluate the demographic data and resolved-relapse rates in clinical follow-up of patients whose antiseizure medications (ASM) were discontinued after a minimum of 2 years of seizure fre...

Parental stress, coping mechanisms and predictors of parental stress among parents of children with epilepsy [2024] - 452KB
by S Hemalatha, B Vengamma, M Nagarathnam, S A A Latheef
Objectives: To investigate the parental stress and coping mechanisms in parents of children with epilepsy (CWE) and to determine the predictors of parental stress. Methods: Parents of CWE (n=323) were...

Giant axonal neuropathy: A rare disease hidden in polyneuropathy [2024] - 723KB
by Arzu Eroglu, Huseyin Caksen
Background& Objective: Giant axonal neuropathy (GAN) is a serious progressive neurodegenerative disease. The aim of this study is to evaluate the frequency and phenotypic-genotypic characteristics of ...

Impact of neuropathic pain on sleep quality in earthquake-related peripheral nerve injuries [2024] - 491KB
by Sıdıka Büyükvural Şen, Emine Çetin, Emine Aygül Ortaç
Objective: Natural disasters such as earthquakes often cause sleep disorders in affected individuals. Neuropathic pain seen in traumatic peripheral nerve injuries has been found to be associated with ...

Decreased serum IL-16 and increased serum TSG-14 levels in myasthenia gravis [2024] - 849KB
by Linqi Liu, Wenjun Que, Rui Fan, Dan Lu, Fei Xiao
Background: Myasthenia gravis (MG) is an autoimmune disease characterized by an imbalance between inflammatory mediators and immune cells. The diagnosis and assessment of disease severity require the ...

Inferring microarray datasets reveals critical biomarkers and potential drug targets of Parkinson’s disease [2024] - 995KB
by Anuradha Bhardwaj, Ahmad A Obaid, Anmar Anwar Khan, Mahendra P Singh, Mohammed M Jalal, Zuhair M Mohammedsaleh, Mamdoh S Moawadh, Walaa F Alsanie, Abdulhakeem S Alamri, Majid Alhomrani, Abdulaziz Alsharif, Sandeep Kumar Singh
Parkinson’s disease (PD) is a critical neurological disorder characterized by loss of voluntary motor control and substantial slowing of movement. While traditionally attributed to environmental fac...

Evaluation of atrophy after botulinum toxin injection in cervical dystonia by MRI [2024] - 525KB
by Mehri Salari, Samaneh Parvizi, Hamidreza Haghighatkhah, Iman Elahi Vahed, Payam Fattahi, Mohammadamin Sabbagh Alvani, Yashar Kheirolahkhani, Mohammadreza Mafi Balani, Masoud Etemadifar, Ronak Rashedi
Objectives: Cervical dystonia (CD) is one of the most common forms of dystonia seen clinically, Botulinum neurotoxin type A (BoNT) is known as the first-line therapy for CD. One of the most critical s...

Utility of high-dose clonidine in managing pediatric dystonia: A case series in a multi-ethnic Asian population [2024] - 368KB
by Guo Yong Lim, Zhi Min Ng, Ling Ying Tan, Tong Hong Yeo
Background: Dystonia is a debilitating movement disorder. Clonidine, an alpha-2 agonist, is reported to be beneficial for pediatric dystonia. The use of high-dose clonidine remains poorly documented. ...

Evaluation of the retina and optic discs of patients with chronic and episodic migraine using optical coherence tomography and optical coherence tomography angiography [2024] - 434KB
by Buket Özkara Yılmaz, Ali Karnaz
Objective: Migraine is a very common, recurring, usually unilateral, severe, pulsating, and transient headache disorder, which causes temporary disability. Abnormal retinal and optic disc pathologies ...

Pattern of cognitive deficit in vascular dementia [2024] - 295KB
by Junita Maja Pertiwi, Ansye Grace Nancy Momole, Finny Warouw, Gilbert Tangkudung, Aristo Rinaldi Pangestu, Glensy Iroth
Background: Vascular dementia (VaD) is the second most common cause of dementia after Alzheimer’s disease. Vascular dementia has heteregeneous manifestation due to varying infarct location and subty...