Neuroimaging in dementia syndromes

Authors

  • Kartini Rahmat Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia https://orcid.org/0000-0001-8513-9076
  • Affendi Haris Phuah Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia
  • Norlisah Ramli Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia https://orcid.org/0000-0001-7497-8093
  • Nadia Fareeda Muhammad Gowdh University Malaya
  • Wai Yee Chan Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia https://orcid.org/0000-0002-2718-3797
  • Maw Pin Tan Division of Geriatrics, Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia https://orcid.org/0000-0002-3400-8540

DOI:

https://doi.org/10.54029/2022aym

Keywords:

dementia, magnetic resonance imaging (MRI), perfusion imaging, functional imaging, cognitive dysfunction

Abstract

Neuroimaging is essential for early diagnosis of different types of dementia. Structural imaging is recommended for patients with new-onset cognitive impairment and magnetic resonance imaging is the modality of choice. When atypical features are present, functional and molecular imaging is helpful for further characterisation of neurodegenerative changes. Accurate identification of dementia subtypes enables early initiation of specific molecular targeted therapies. This article provides an overview of the structural, biochemical and functional changes in common dementia subtypes that may be diagnosed through neuroimaging, emphasising new techniques like perfusion and functional imaging.

Published

2022-12-26

Issue

Vol. 27 No. 4 (2022)

Section

Views and Reviews