Serum neurofilament level as a biomarker in multiple sclerosis [2024] - 458KB
by Huda Qate’a Jabbar, Hayder K Hassoun, Zuhair Allebban
Background & Objective: Currently, MS disease activity and neurodegeneration are assessed mainly through clinical evaluation and magnetic resonance imaging. These measures lack sensitivity and specifi...

Direct cost of rituximab treatment in multiple sclerosis: A real-world finding from Malaysia [2024] - 329KB
by Sutha Rajakumar, Vijitha Rajendran, Mohamed Azlam Mohamed Micdhadhu, Irene Looi, Retha Rajah
Background & Objective: Multiple sclerosis (MS) imposes a significant economic burden on the healthcare system. In 2022, more than half of the Neurology budget of Hospital Seberang Jaya was spent on r...

Study of the association between anemia and prognosis of moderate-to-severe traumatic brain injury [2024] - 404KB
by Ruilan Yin, Xijian Wei
Objective: To investigate the impact of admission anemia on the prognosis of patients with moderate- to-severe traumatic brain injury (TBI). Methods: The clinical data of patients with moderate-to-sev...

Indicators of abnormal CT Scan findings in clinically mild traumatic brain injury patients [2024] - 276KB
by Erwin W Nugraha, Melke J Tumboimbela, Denny J Ngantung, Windy M V Wariki, Rizal Tumewah, Finny Warouw
Background & Objective: Various clinical guidelines have been developed to predict intracranial findings and minimize the unnecessary head CT scans in mild traumatic brain injury (MTBI) patients. Howe...

MAD2L2 as a novel prognostic biomarker and its correlation with immune infiltrates in glioma [2024] - 3,735KB
by Kaiqin Chen, He Li, Yongtai Chen, Hesen Huang
Background: The most common type of central nervous system tumor is glioma, the identification of Glioma biomarkers is essential. MAD2L2, which is abbreviated as MAD2-Like2, collaborates with a number...

Childhood vertigo: A retrospective series of 791 cases [2024] - 606KB
by Zülal Özdemir Uslu, Didem Ardıçlı, Deniz Yılmaz
Background: Vertigo is one of the most common complaints leading to admissions in pediatric neurology clinics. Diagnosis of vertigo in children is often challenging due to limited communication capaci...

A novel aptamer agent showed antidepressant function via binding 5-hydroxytryptamine receptor to block re-uptake of 5-HT [2024] - 1,045KB
by Zhiding SHAO, Renrui HAN, Ying HUA, Jian HU Xia REN, Fan SU, Xiaolei TANG
Background & Objectives: Systematic evolution of ligands by exponential enrichment (SELEX) technology was widely used to screen the aptamers that bind the target protein safely and efficiently. Our st...

Very early re-do microvascular decompression for patients with trigeminal neuralgia [2024] - 507KB
by Tao Sun, Yu Su, Wentao Wang, Longshuang He, Jinlong Liu, Chao Yang
Although microvascular decompression (MVD) is the widely recognized surgical option for patient with trigeminal neuralgia (TN), and most patients could receive satisfactory outcome, some patients stil...

A case of primary Sjögren syndrome masquerading as post-COVID Bickerstaff encephalitis [2024] - 570KB
by Shawn Zhi Zheng Lin, Hua Chan Ling, You-Jiang Tan
We present a case of acute external ophthalmoplegia, hypersomnolence, and ataxia occurring 5 days after an episode of SARS-CoV-2 upper respiratory tract infection. The patient’s serum returned posit...

Adult-onset Krabbe disease manifesting as Charcot- Marie-Tooth disease [2024] - 918KB
by Jin San Lee, Jin Ho Jung, Go Hun Seo, Eunkyoung You, Seong-il Oh
Krabbe disease (KD) is a progressive lysosomal storage disorder characterized by the deficiency of β-galactocerebrosidase (GALC). It mainly manifests as central nervous system involvement, but periph...