A retrospective clinical trial of gabapentin combined with duloxetine for the treatment of neuropathic pain after maxillofacial fracture [2025] - 1,185KB
by Jianhong Zhou, Yong Li
Background & Objectives: Neuropathic pain (NPP) following a maxillofacial fracture can decrease patients’ quality of life and lead to numerous mental and psychological issues. However, using gabapen...

Effectiveness of acceptance and commitment therapy for reducing emotional burden in family caregivers of patients with dementia: A pilot study [2025] - 466KB
by Jiyoung Gwak, Jinse Park
Background & Objective: Recently, psychoeducational support to caregivers of patients with dementia (CPWD) has attract much interested. Acceptance and commitment therapy (ACT) which accept negative th...

Estrogen-related gene INPP5D is a potential biomarker for Alzheimer’s disease [2025] - 1,989KB
by Qiao-Qiao Wang, Lili Guo, Cheng Yan, Cha-Ying He
Objective: This study aims to leverage bioinformatics methodologies to screen genes related to Alzheimer’s disease (AD) and estrogen, unravel the interplay between estrogen and Alzheimer’s pathoph...

Clinical features of antibody-negative autoimmune encephalitis: A meta-analysis and literature review [2025] - 774KB
by Weiwei Gao, Jingjing She, Lijuan Cai, Lihong Su, Yifen Zhang, Shuixian Li, Xingyu Chen, Renjing Zhu
Objective: This study aimed to conduct a comprehensive literature review and meta-analysis of antibody-negative Autoimmune encephalitis (AE) and to quantitatively compare the clinical features of anti...

Investigation of exercise barriers-benefits, kinesiophobia, physical activity, fatigue and depression in individuals with multiple sclerosis [2025] - 442KB
by Fatih Özden, Mehmet Özkeskin, Ece Ekici, Nur Yüceyar
Background & Objective: Despite the benefits of exercise for individuals with multiple sclerosis (MS), physical activity levels in people with MS (pwMS) remain lower than in healthy controls. Identify...

Real-world experience of ocrelizumab in patients with multiple sclerosis: A single-center study [2025] - 529KB
by Koc Emine Rabia, Turan Omer Faruk, Saridas Furkan, Ceylan Dursun, Ozkaya Guven
Objective: We aimed in this study to obtain real-world data in MS patients treated with ocrelizumab at our center and examine the drug’s efficacy, safety, and side effects. Methods: We conducted a r...

Challenges faced by pediatric patients with multiple sclerosis during disease progression and treatment: A multicenter cross-sectional study in Türkiye [2025] - 467KB
by Didem YÜKSEL, Figen YARDIMCI
Background & Objective: Multiple sclerosis is a chronic and progressive disease characterized by inflammation, demyelination and degeneration of the central nervous system. This study aimed to describ...

Analysis of clinical features and literature review of myelin oligodendrocyte glycoprotein antibody-associated disease [2025] - 1,063KB
by Bo Liu, Haixiang Wu, Shujuan Yang, Qingcheng Yang, Xiangdong Zhang
Objective: The purpose of this study is to analyze the clinical features of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Methods: A retrospective analysis was conducted on ...

Xueshuantong improves therapeutic outcome and quality of life of elderly patients with benign paroxysmal positional vertigo after Epley maneuver [2025] - 596KB
by Xiaojiang Zhang, Jingrong Miao, Chunyan Dai
Objective: Benign paroxysmal positional vertigo (BPPV) is a common peripheral vestibular disorder. This study aimed to evaluate the therapeutic effect of Xueshuantong in patients with BPPV treated wit...

The warning criterion of intraoperative bulbocavernosus reflex monitoring in adult patients with lumbosacral intraspinal tumor [2025] - 931KB
by Tuanfeng Yang, Jia Lu, Kehan Jin, Desheng Kong, Yanxiang Wang, Xianzeng Liu
Objective: There are currently no standard warning criteria for intraoperative neurophysiological monitoring (IONM) of bulbocavernosus reflex (BCR). This study aimed to preliminary detect a practical ...