Factors affecting aquaporin-4 and its regulatory mechanisms in Alzheimer’s disease [2025] - 444KB
by Qianqian YAO, Hailang LI, Hexu LIU, Ye YANG, Changyin YU
Alzheimer’s disease (AD) is a common neurodegenerative disorder, with its core pathological features being the excessive deposition of amyloid-beta (Aβ) protein and the abnormal phosphorylation of ...

Impact of clopidogrel resistance on stroke severity in patients with acute ischemic stroke [2025] - 472KB
by Yoon Jung Kang, Sang Min Sung, Sang Won Han, Han-Jin Cho
Background: Prior use of antiplatelet agents is associated with reduced severity in patients with ischemic stroke. However, clopidogrel resistance, which is characterized by a suboptimal platelet resp...

The importance of panimmune inflammation value and systemic immuno-inflammation index in patients with acute cerebrovascular infarction [2025] - 682KB
by Muhammed Kamiloğlu, Keziban Uçar Karabulut, Meltem Karacan Golen, Alpaslan Kısınma, Yildiz Ucar
Background: Stroke is a condition that negatively affects the quality of life in all societies and is one of the leading causes of mortality in adults. It is the second most common cause of death and ...

Evaluation of the performance of pan-immune inflammation value in predicting in-hospital mortality in patients with spontaneous intracerebral hemorrhage [2025] - 536KB
by Hazal Zeynep Daduk, Fatma Ebru Algul, Yuksel Kablan
Background & Objective: Spontaneous intracerebral hemorrhage (ICH) is associated with high mortality and poor functional prognosis. This study aimed to evaluate the prognostic significance of the pan-...

Dynamic changes of systemic immune-inflammation index and systemic inflammation response index after mechanical thrombectomy and their predictive value for functional outcomes in patients with acute ischemic stroke [2025] - 1,061KB
by Jingjing She, Weiwei Gao, Yanan Zhao, Lijuan Cai, Hua Ge, Xingyu Chen, Zhongjie Chen, Renjing Zhu
Objective: To investigate the dynamic changes in the systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) after mechanical thrombectomy (MT) and their ability to pr...

Evaluation of three minimally invasive surgical techniques for hematoma removal in elderly patients with hypertensive intracerebral hemorrhage: A pilot randomized study [2025] - 502KB
by Shiping Chen, Yuning Feng, Cheng Chen
Objective: To compare the efficacy and safety of three minimally invasive surgical (MIS) techniques— neuroendoscopic hematoma removal, minimally invasive soft channel puncture and drainage, and smal...

Association between baseline cognitive function and motor improvement in subacute hemiplegic stroke patients after 4 weeks of rehabilitation [2025] - 488KB
by Eun Chae Lee, SeoYeon Yoon, Hyun Im Moon, Soo Jeong Han, Jee Hyun Suh
Background & Objectives: Motor function and cognition are crucial for performing daily activities in patients with stroke. However, it remains unclear whether measures of motor function in patients wi...

Evaluation of the thalamus volume and cortical thickness in patients with epilepsy and determining the relationship of these measurements with the clinical variables of the disease [2025] - 523KB
by Tuğçe Güven Ekiz, Özlem Akdoğan, Ece Ateş Kuş, Aygül Tantik Pak, Ufuk Emre Toprak
Background & Objectives: The influence of cortical firing neurons and subcortical structures, especially thalamic networks, has a role in the formation and continuity of epileptic seizure activities. ...

The presence of sleep apnoea and evaluation of sleep structures in epilepsy subtypes [2025] - 798KB
by Kübra Mehel Metin, Selda Keskin Güler, Tahir Kurtuluş Yoldaş
Background & Objective: Identifying seizure-triggering factors and taking precautions in epilepsy patients are important for seizure control and disease progression. Comorbidity between sleep disorder...

The prevalence and impacts of psychological disorders in caregivers of Chinese ALS patients [2025] - 706KB
by Nan Hu, Dongchao Shen, Xunzhe Yang, Jingwen Niu, Liying Cui, Mingsheng Liu
Objective: To investigate the prevalence and influential factors of depression, anxiety, suicidal tendency and sleep disorders in caregivers of Chinese amyotrophic lateral sclerosis (ALS) patients. Me...