Risk of stroke in Alzheimer’s disease: A meta-analysis

Authors

  • Juan Liu
  • Xiaomeng Wang
  • Yanni Ru
  • Na Yang
  • Yufeng Zhang
  • Bei Zhang Department of Neurology，The First Affiliated Hospital of Xi'an Medical University

DOI:

https://doi.org/10.54029/2024jkp

Keywords:

alzheimer’s disease, stroke, age, DALY, ischemic stroke, hemorrhagic stroke

Abstract

Background: Stroke occurs when a blood vessel of the brain narrowed or completely blocked. Stroke and Alzheimer’s disease (AD) are the commonest diseases in elderly. Some studies confirm the association between AD and the increased risk of stroke.

Methods: In present meta-analysis we conducted a systematic analysis on risk of stroke in AD patients. A thorough literature search was conducted using different databases, including Google Scholar and MEDLINE. The present metanalysis includes all the studies published from 2010 to 2023. We found more than 57,260 matching results and five were relevant to our area of interest and met all the selection criteria.

Results: All the selected studies confirm the association of stroke with AD. The AD patients were al higher risk of stroke (ischemic and haemorrhagic) than the normal individuals.

Conclusion: Present meta-analysis confirms the significant association of AD with stroke. There were only five studies available. To validate the results further evidences are required.

Published

2024-10-05

Issue

Vol. 29 No. 3 (2024)

Section

Original Article