A Case Report: Numbness and Prolonged Anosmia in a COVID-19 Patient and the Possibility of Small Fiber Neuropathy

Abstract

Numbness or polyneuropathy was rarely reported as the presenting sign nor a common finding in COVID-19 cases. On the other hand, recent reports suggest that SARS-CoV-2 can cause olfactory dysfunction. Furthermore, impairment in olfactory and gustatory function has been recognized as one of the presenting signs of COVID-19. However, although polyneuropathy and olfactory disorders originate from a peripheral nerve disorder, no study has been addressed to discuss the possible interaction between these two symptoms and the role of small nerve fiber disorder in their pathomechanism. 

We report a 42 years old female with COVID-19 who experienced numbness and prolonged hyposmia. The possible interaction of these two findings is discussed with the possibility of small nerve fibers disorder.