Pharmacotherapeutic potential of soy isoflavones in neurological disorders

Authors

  • Melika Mokhtari Student Research Committee, Dental Faculty, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  • Fatemeh Qolipour Student Research Committee, School of Medicine, Ardabil Branch, Islamic Azad University, Ardabil, Iran
  • Amir Hossein Yousefi Student Research Committee, Babol University of Medical Sciences, Babol, Iran
  • Dorsa Alijanzadeh Student's Research committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Qumars Kasnavi Student's Research committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Tina Sadeghi Student's Research committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Diba Akbarzadeh Student's Research committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Mohammad Sadegh Fallahi School of medicine, Tehran University of Medical Sciences
  • Niloofar Deravi Student's Research committee, School of medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.54029/2022psy

Keywords:

neurological disorder, isoflavones, genistin, daidzin, complimentary medicine, natural compound

Abstract

In specific populations, soy products have been a part of their diet for many centuries. Soybeans are known to be beneficial mostly because of being rich sources of isoflavones. Various studies showed that Soy isoflavones such as daidzein and genistein have positive effects on gastrointestinal health, cancer prevention, and health promotion in postmenopausal women. In recent years, many studies focused on the neuroprotective effects of soy isoflavones in animal models and humans. This review includes the latest literature on the effects of soy isoflavones in various neurological disorders. In conclusion, soy isoflavones have neuroprotective, anti-inflammatory, and anti-oxidant effects and can be used to prevent stroke, improve memory and cognitive function, reduction of Parkinson’s disease symptoms, and also as a therapeutic agent in multiple sclerosis.

Published

2022-10-01

Issue

Vol. 27 No. 3 (2022)

Section

Views and Reviews