Authors
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Bora Chung
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
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Chan Hyun Lee
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
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Eunji Kim
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
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Minjun Kim
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
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Minjung Kim
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Oh-Young Kwon
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea, Institute of Health Science, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
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Do-Hyung Kim
Department of Neurology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea
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Tae-Won Yang
Department of Neurology, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Korea
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Jongsoo Kang
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
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Young Soo Kim
Department of Neurology, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea, Institute of Health Science, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
https://orcid.org/0000-0003-1040-372X
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Hyun Park
Department of Neurosurgery, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Republic of Korea, Institute of Health Science, Gyeongsang National University College of Medicine, Jinju, Republic of Korea
Keywords:
status epilepticus, nonconvulsive status epilepticus, vagus nerve stimulation
Abstract
Super refractory status epilepticus (SRSE) is a condition in which status epilepticus persists despite 48 hours of anesthetic treatment. Nonconvulsive status epilepticus (NCSE) is characterized by seizures lasting more than 30 min on an electroencephalogram, with accompanying changes in behavior or consciousness without convulsions. Prompt treatment of NCSE is crucial, as delayed treatment may lead to additional brain damage and progression to convulsive status epilepticus. Although vagus nerve stimulation (VNS) has been approved as an adjunct treatment for drug-resistant epilepsy, it is rarely used to treat refractory status epilepticus. To the best of our knowledge, only two cases of NCSE treated with VNS have been reported to date, and these patients were successfully treated with VNS for NCSE caused by anti-NMDAR encephalitis. We report the case of a patient with posttraumatic epilepsy who developed super refractory-NCSE after convulsive status epilepticus and was successfully treated with VNS.
